May 20, 2013

Preventing Alzheimer's Disease-Related Brain Shrinkage

Preventing Alzheimer’s disease-related brain shrinkage by B-vitamins:

In this Blog we will look at the latest Oxford University research study concerning homocysteine and dementia.

It concerns the protective effect of high doses of B-vitamins in slowing brain shrinkage.


What was already known:

Previous OPTIMA findings, concerning brain shrinkage and cognitive decline, were discussed in our earlier blogs.

It had been shown that High Dose B-Vitamins slow brain shrinkage in patients with Mild Cognitive Impairment and raised homocysteine.

The latest study sought to determine exactly which areas of grey matter in the brain were protected by B-vitamins.


What the latest study found:

The study used MRI Brain Scans from 156 subjects to investigate this.  80 patients received high dose B Vitamins, as used in Betrinac, and 76 received a placebo.

The researchers found that B-vitamins slowed shrinkage specifically in those areas of the brain affected by the Alzheimer’s Disease process.

B-vitamins reduced brain shrinkage by as much as seven-fold in these especially vulnerable brain areas.


How B-Vitamins in Betrinac slow cognitive decline:

The latest study also took a closer look at the likely sequence of events in treated patients.

B-vitamins lowered homocysteine; homocysteine lowering then directly led to slowed gray matter shrinkage.

As a result, B-vitamins ultimately slowed cognitive decline.



High doses of B-vitamins used in Betrinac slow shrinkage in specific brain regions affected by Alzheimer’s Disease.

The result? A slowing down of any associated cognitive or memory decline.


Older article Blog index Newer article